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Abstract Suppressing errors is the central challenge for useful quantum computing¹, requiring quantum error correction (QEC)^2–6for large-scale processing. However, the overhead in the realization of error-corrected ‘logical’ qubits, in which information is encoded across many physical qubits for redundancy^2–4, poses substantial challenges to large-scale logical quantum computing. Here we report the realization of a programmable quantum processor based on encoded logical qubits operating with up to 280 physical qubits. Using logical-level control and a zoned architecture in reconfigurable neutral-atom arrays⁷, our system combines high two-qubit gate fidelities⁸, arbitrary connectivity^7,9, as well as fully programmable single-qubit rotations and mid-circuit readout^10–15. Operating this logical processor with various types of encoding, we demonstrate improvement of a two-qubit logic gate by scaling surface-code⁶distance fromd = 3 tod = 7, preparation of colour-code qubits with break-even fidelities⁵, fault-tolerant creation of logical Greenberger–Horne–Zeilinger (GHZ) states and feedforward entanglement teleportation, as well as operation of 40 colour-code qubits. Finally, using 3D [[8,3,2]] code blocks^16,17, we realize computationally complex sampling circuits¹⁸with up to 48 logical qubits entangled with hypercube connectivity¹⁹with 228 logical two-qubit gates and 48 logical CCZ gates²⁰. We find that this logical encoding substantially improves algorithmic performance with error detection, outperforming physical-qubit fidelities at both cross-entropy benchmarking and quantum simulations of fast scrambling^21,22. These results herald the advent of early error-corrected quantum computation and chart a path towards large-scale logical processors. 

Quantum machine learning has gained considerable attention as quantum technology advances, presenting a promising approach for efficiently learning complex data patterns. Despite this promise, most contemporary quantum methods require significant resources for variational parameter optimization and face issues with vanishing gradients, leading to experiments that are either limited in scale or lack potential for quantum advantage. To address this, we develop a general-purpose, gradient-free, and scalable quantum reservoir learning algorithm that harnesses the quantum dynamics of neutral-atom analog quantum computers to process data. We experimentally implement the algorithm, achieving competitive performance across various categories of machine learning tasks, including binary and multi-class classification, as well as timeseries prediction. Effective and improving learning is observed with increasing system sizes of up to 108 qubits, demonstrating the largest quantum machine learning experiment to date. We further observe comparative quantum kernel advantage in learning tasks by constructing synthetic datasets based on the geometric differences between generated quantum and classical data kernels. Our findings demonstrate the potential of utilizing classically intractable quantum correlations for effective machine learning. We expect these results to stimulate further extensions to different quantum hardware and machine learning paradigms, including early fault-tolerant hardware and generative machine learning tasks